Ruthenium-Free Preparation of 1,5-Disubstituted Triazoles by Alkylative Debenzylation of 1,4-Disubstituted Triazoles
نویسندگان
چکیده
منابع مشابه
Synthesis of 2-tetrafluoropyridyl-4,5-disubstituted 1,2,3-triazoles
ABSTRACT By cycloaddition reaction of sodium azide with chalcone in the presence of CuO as a catalyst in DMF a 1,2,3-triazole are prepared in reaction with pentafluoropyridine to give 2-(tetrafluoropyridin-4-yl)-1,2,3-triazole derivatives in good yields and high regioselectivity. The regioselectivity of the compounds are confirmed by 19F-NMR and other spectroscopy. GRAPHICAL ABSTRACT
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ژورنال
عنوان ژورنال: Synlett
سال: 2016
ISSN: 0936-5214,1437-2096
DOI: 10.1055/s-0035-1562603